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The treatment comparison reveals GHK-Cu discontinuation profile proving more favorable than retinoids (less dependency, no rebound, better benefit retention) while similar to vitamin C and niacinamide (gradual decline, moderate long-term retention, low dependency)

16 h: n = 3)

Chemical Makeup (2) (2) Molecular Formula: C 15 H 25 CuN 6 O 4 Molecular Weight: 416.9 g/mol Other known titles: ALA-HIS-LYS-CU, L-Alanyl-N-L-histidyl-N,N3-L-lysinato(2-)]copper Monohydrochloride Research and Clinical Studies AHK-Cu Peptide and Antioxidative Potential AHK-Cu is posited to have potent antioxidant qualities, primarily due to its distinct amino acid structure

10.1055/s-0036-1571297 129 SinghV.KeishamA.BhallaA.SharmaN.AgarwalR.SharmaR.et al (2018)