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Canonically, it controls BA homeostasis by regulating genes involved in BA synthesis (CYP7A1, CYP8B1), transport (BSEP, ASBT, OST/), and feedback regulation (SHP, FGF15/19) (84, 85, 90)
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A clearer understanding of how genetic variants associated with MASLD interact with sex and reproductive status will allow for risk stratification of MASLD progression at the time of menopause
Furthermore, in a series of different injurious models, acute and chronic, 1 - 13 BPC 157 consistently promotes healing after severe injuries in various tissues which are spontaneously unable to heal
