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(More information) The preservation of DNA integrity is dependent on folate and vitamin B 12 availability

J.et al (2018)

Tendon and ligament healing Due to a limited blood supply, the spontaneous healing of both tendons and ligaments is inherently poor

A decreased HoloTC level along with an increase in the size of the red blood cells (macrocytosis) is a good measure of vitamin B12 deficiency
