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Several CpG islands (regions rich in cytosine and guanosine residues) have been identified in the CSE promoter, which are hypermethylated in patients with coronary artery disease

While investigating the potential mechanisms and interactors through which TB4 may be influencing myocardial cell migration and survival events via phage display, we proved ILK-mediated Akt activation to inhibit myocadial cell death may be one of the role players in the process