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TF neutralizes iron-induced toxicity in iRPE cells Because lipid peroxidation leads to iron overload in iRPE cells, we further investigated the mechanisms of action of TF on iRPE cells exposed to FeCl 3 associated with nitrilotriacetate, which forms a stable iron complex in solution
238 However, other works have demonstrated that SIRT2 promotes cancer growth by stabilizing the Myc family of oncoproteins 239,240 and enhancing the signaling of the Notch pathway
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