glutathione s-transferase detoxification and MRP1 form an integrated system involved in the storage and transport of dinitrosyl–dithiolato iron complexes in cells Role of Glutathione in detoxification

These factors include homeostatic iron regulator (HFE)

In a first part, I discuss biological issues related to the persistence of microbial antigens, dysregulated immune responses, reactivation of latent viruses, different potential self-sustained inflammatory loops, mitochondrial dysfunction, metabolic disorders in the tryptophan- kynurenin pathway (TKP) with impact on serotonin, and consequences of a dysfunctional bidirectional microbiota-gut-brain axis

However, keep in mind that the type of hyperpigmentation youre targeting can matter

According to various studies, individuals with major depressive disorder (MDD) are more likely to engage in excessive alcohol consumption