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Epub 2018/10/09

However, we caution against excessive interpretation of our complementation data on MurJ TA as well as previous mutagenesis data on MurJ EC as these experiments cannot determine the exact functional roles of these residues

The first vaccine, developed by Sanofi Pasteur, used formalin-inactivated full-length toxins TcdA and TcdB, but the vaccines development was halted after phase III clinical trials

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