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M.AriE.et al

4 Tolerability in year 2 is underappreciated Amgen noted year-two treatment was very well tolerated on the quarterly dose (full data still pending)

2025;6:e70152

While canonical ferroptosis regulation centers on cystine uptake and GPX4-mediated GSH utilization, the endogenous metabolic pathways governing ferroptosis sensitivity in liver tumors remain incompletely understood
