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Description
Houston, 2005

This study establishes a patterned iPSC-derived sensory neuronal circuitry between DRG organoid (DRGO) sensory neurons and muscle intrafusal fibers, offering an improved in vitro model for studying FRDA pathology and investigating potential therapeutic interventions, such as CRISPR/Cas9-mediated removal of trinucleotide expansions in the FXN gene intron

(ii) In the case of smokers blindness or Lebers optic atrophy, the usual starting dose is at 1,000 micrograms daily for 2 weeks, the twice weekly PROVIDED YOU ARE RESPONDING WELL

J., Smith, A
