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An early cross-sectional study of 101 fertile and infertile men found that L-carnitine concentrations in semen were positively correlated with the number of sperm, the percentage of motile sperm, and the percentage of normal appearing sperm in the sample (110), suggesting that L-carnitine may play an important role in male fertility

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PCC is a biotin-dependent enzyme located in the mitochondrial matrix involved in the metabolism of propionate, an intermediary metabolite from the breakdown of 4 essential amino acids (methionine, threonine, valine, isoleucine), odd-chain fatty acids and the side chain of cholesterol

It is often associated with active lifestyles because it plays a role in energy metabolism