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The key is that the whole process has to be a lot slower

Gene Family of -Glutamyltransferase Although GGT had long been considered a unique enzyme with -glutamyl bond-cleaving activity, particularly with respect to glutathione metabolism, another closely related but clearly different enzyme, referred to as the GGT-related enzyme (GGT-rel), is known to catalyze the hydrolysis of glutathione [96]

For researchers developing small-molecule inhibitors, nucleic acid therapeutics, uricosuric agents, or anti-inflammatory biologics, choosing the right animal model can directly influence the interpretability and translational value of preclinical data

Veldhuis JD, Evans WS, Bowers CY, Anderson S