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Studies using beta-3 adrenergic receptor knockout mice confirmed the specificity of this mechanism, as these animals showed no fat loss response to AOD-9604
doi: 10.1079/BJN19780122
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AOD 9604 Studies on Obesity Models In obese murine models, both growth hormone and AOD 9604 have been linked to reductions in body fat mass, though the outcomes appeared different in lean models
