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Arch Med Res 34(2):8999
Mayo Clin Proc 88(6):544551
The study was conducted in accordance with the Declaration of Helsinki, and the protocol was approved by the Independent Bioethics Commission for Research at Medical University of Gdansk Ethics (NKBBN/354-304/2015)
Obesity represents itself as a challenge for hypothalamus-pituitary-thyroid axis since it has been hypothesized that hyperleptinemia, that often characterizes these patients, may increase the expression of TRH gene and thus TSH secretion [194]
