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This stands in marked contrast to what has happened in different situations in which clinical trials were designed according to predictive biomarkers such as, e.g., trastuzumab in HER2-positive breast cancer patients

| 05.22.26 | 13 min read

Two patients (Figure 4) with vitamin B12 deficiency who developed hypersensitivity reactions during treatment with commercially available vitamin B12 were included in the intramuscular desensitization protocol [11]

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