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Following irradiation, foretinib-treated cells had diminished repair of DNA double-stranded breaks and underwent more apoptosis

& Deltenre, P

These data provide a rationale to increase the efficacy of conventional chemotherapies combined with antioxidant therapies for ovarian cancer

Therefore, these aforementioned studies suggest that the RNA m 6 A modification is involved in ferroptosis by regulating the mRNA stability and protein expression of multiple ferroptosis-related genes (Figure 4B)