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Based on its nucleoside analogue structure, it is tempting to speculate that the drug could impair mitochondrial DNA replication and induce a mitohormetic response ( Taken together, the various effects of rapamycin and adefovir dipivoxil observed here suggest that modulating the expression of both C/EBP- isoforms, LAP and LIP, is likely critical for nutrient homeostasis

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No psammomatous bodies were present

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Filipek et al

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Istradefylline a first generation adenosine A 2A antagonist for the treatment of Parkinsons disease Expert Review of Neurotherapeutics [14737175]

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