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Kim MN, Moon JH, Cho YM

As the ER lacks glutathione reductase activity, GSSG must be exported to the cytosol by SLC33A1 to maintain redox homeostasis

In cell culture models of human macrophage foam cells, the inability to clear cholesterol from macrophages with compromised lysosome function continues even in the presence of compounds that stimulate efflux (161,163)
