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Astaxanthin reduces the expression of FN, ICAM-1, and TGF-1 induced by HG to reduce ECM deposition, and significantly promotes the nuclear translocation and transcriptional activity of Nrf2, and induction the expression of HO-1 [149, 150]

10.1016/S2213-2600(22)00492-1 [DOI] [PubMed] [Google Scholar] 194.Corren J, Menzies-Gow A, Chupp G, et al

Interestingly, the deletion of NOX2 following mouse TBI (Wang et al., 2018) or PTZ-induced SE ( 2 and resulting increased steady-state H 2 O 2 levels is necessary for NF-KB activation in macrophages (Li et al., 2018) and for microglia proliferation (Mander et al., 2006)

Remove any air bubbles by gently tapping the syringe and pushing them back into the vial before withdrawing your needle