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Description

However, in FUS-induced ALS/FTD, FUS is hypomethylated and accumulates in neurons as both nuclear and cytoplasmic aggregates

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Reported effects from preclinical and unregulated human use: Nausea (anecdotal, from community reports) Dizziness (rare, anecdotal) Injection site reactions (bruising, redness) Headache (rare) Theoretical concern about VEGF-mediated tumor angiogenesis Teduglutide Side Effects# Well-characterized from clinical trials: Monitoring requirements : Teduglutide requires colonoscopy within 6 months of starting and then every 5 years due to theoretical risk of intestinal polyps or neoplasia from chronic intestinal proliferation