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The results of a prior study confirmed the protective benefits of L-carnitine due to suppression of inflammation, oxidative stress, and increased autophagy (Khedr and Werida 2022)

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[70] utilized carnitine-conjugated nanoparticles to improve the efficacy of paclitaxel delivery in glioma cells

Several subclasses of these former T-regs have been identified in the atherosclerotic lesions of mice, including Th1-Tregs (CD4 + CCR5 + IFN- + FoxP3 + T-bet + ) and T follicular helper cells (CXCR5 + PD1 + Bcl6 + CD62L lo CD44 hi CD4 + Foxp3 - ), and these have been shown to have both impaired regulatory and enhanced inflammatory function, therefore contributing to atheroprogression (91,92)