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Administration of intravenous thiamin to WKS patients generally results in prompt improvement of the eye symptoms, but improvements in motor coordination and memory may be less, depending on how long the symptoms have been present

Exposure to stress at 6 h caused a 30-fold increase in expression of the CTT1 gene at 45 min, an activation that was much lower than that observed upon entry into the stationary phase ( Figure 3 )

Phase II Prospective Clinical Validation: A more robust, translational validation, focusing on the Asian population, is being prepared through a prospective, multi-center study

Proteomics 9:409419 Yamamoto T, Kikkawa R, Yamada H, Horii I (2006) Investigation of proteomic biomarkers in in vivo hepatotoxicity study of rat liver: toxicity differentiation in hepatotoxicants