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Clinical studies specifically monitoring glucose metabolism through oral glucose tolerance tests found no significant changes in glucose handling, and fasting insulin levels remained stable throughout treatment periods lasting up to 24 weeks
A recently published longitudinal study showed that people using metformin had a greater risk of neuropathy [HR = 1.84 (95% CI, 1.62, 2.10)] than those not using metformin [49]
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[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Randaccio L., Geremia S., Demitri N., Wuerges J
