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Additionally, while preclinical studies have demonstrated encouraging results, most research remains in early stages, and the lack of reliable biomarkers for monitoring ferroptosis complicates clinical application

However, in the presence of an enlarged liver or spleen, petechiae, thrombocytopenia, or other findings suggesting liver or biliary disease, metabolic disease, or congenital infection, bilirubin fractions should be measured

For dogs, curcumin is best absorbed when paired with a small amount of black pepper (piperine), which significantly improves bioavailability

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