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IL-1 and TNF- cause damage to mitochondrial DNA, decreased energy production and mitochondrial transcription, therefore triggering apoptosis in chondrocytes
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a resident pool of immune cells (for example, macrophages and synovial fibroblasts) is stimulated
[DOI] [PubMed] [Google Scholar] 58.Daubeuf S., Leroy P., Paolicchi A., Pompella A., Wellman M., Galteau M.M., Visvikis A
