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Kantarjian HM, O'Brien SM, Keating MJ, Estey EH, Beran M, Koller CA, Kornblau SM , M-B R, Freireich EJ, Talpaz M

Investigator-blinded, single-center study to evaluate the efficacy and tolerability of a 4% hydroquinone skin care system plus 0.02% tretinoin cream in mild-to-moderate melasma and photodamage

Onset tends to be faster than SubQ because of higher tissue blood flow, but injection-site discomfort can be more pronounced

There are two F16 isomers that can specifically display mitochondria in the green and red channels, respectively, due to their unique fluorescence properties, providing new ways of studying mitochondrial targeting by F16