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Criteria for discontinuing or modifying allocated interventions The participants can be withdrawn from the trial at any time with no effect on their ongoing care in case of any major ailment necessitating the institution of new modalities of treatment or in case of non-compliance of the treatment regimen (minimum 80% compliance is essential to continue in the study) or when the blood pressure is not under control

L.MohanyM.MiloeviM.Al-RejaieS

Due to its simple administration and the low risk of complications, autologous bone marrow applied locally and, in particular, intramuscularly administered osteogenous substances such as TRIS-BPC157, are advantageous over other more complex surgical methods (i.e., bone grafts, vascularized bone grafts, method of Ilizarov) for the treatment of healing impairments in humans