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The microbial metabolites, such as SCFAs, are demonstrated to be a key factor in the modulation of the inflammatory pathway, binding to specific receptors that regulate the immune function pathways (5759)

Desferrioxamine (DFOA), an iron chelator, completely covers the surface of Fe 3+ during complex formation, thereby preventing iron-catalyzed free radical reactions [8]

This review describes the currently available pharmacological and nonpharmacological treatments for painful DPN

doi:10.1093/ecam/nem040 References are provided for educational context
