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It has been described in publications that an analogue of this domain, AOD9604, can increase lipolytic sensitivity and affect the expression of receptors beta-3 adrenergic in adipose tissue, and increase fat oxidation and energy expenditure in animal models

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The combination with hyaluronic acid (6 mg) in the rabbit model produced superior outcomes to either compound alone, which has led some practitioners to explore AOD-9604 in joint health contexts