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By bilaterally injecting lentiviral vectors carrying siRNA targeting GSK-3 into the hippocampal dentate gyrus region to modulate GSK-3 activity, the study found that IF promoted neuronal differentiation and maturation in the dentate gyrus and improved the known dysfunction in 3xTg-AD mice

At the Dr Bob Khanna Training Institute, our focus is on evidence-based education, practical clinical skills and ongoing support, helping you leave with the confidence to apply your learning in practice

Limited renal B12 reabsorption may occur with the TCII receptor megalin (Lrp2) transporter