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Description
It was found that both PACAP-38 (pituitary adenylate cyclase-activating polypeptide-38) and PACAP (638) treatment resulted in significant downregulation of complex I subunit B6 expression in primary cultured trigeminal ganglion cells (Takcs-Lovsz et al., 2022), and metabolic changes and mitochondrial dysfunction, such as reduced complex I, III, IV and citrate synthase activities, were detected in migraine patients (Gross et al., 2019)
doi: 10.1097/00004872-200411000-00020
PMID: 105 Wong-RileyMT
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