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The anti- Vibrio compound was structurally characterized as amicoumacin, and the major anti- Vibrio mechanism was disruption of the bacterial cell membrane (Gao et al., 2017
doi: 10.1016/j.cellsig.2012.01.008 116
Mast cells produce interferon- (IFN) and IL-6 and appear to promote lesion development (90)
Caffeine, the major coffee component, is reported to act as an antioxidant to scavenge hydroxyl radical (OH) and inhibit oxidative stress (21)
