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Description
Kim et al., 2006)

Genetic fate tracking with Esm1-CreERT2 transgenic mice has established that tip cell progeny contributes to the arterial but not the venous branch of the vasculature, which involves signaling interactions via the Notch pathway, the chemokine receptor CXCR4 and its ligand CXCL12, and interactions between ephrin-B2 and its receptor EphB4 11,12,13

In old rats, growth hormone-releasing peptide-6 returned the levels of GH and IGF-I secretion and liver IGF-I mRNA and partially restored the lower pituitary IR-GH and GH mRNA levels to those of young untreated rats

Helps maintain cardiovascular health
