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Diols In 1983, Hamberg reported on the hemoglobin-catalyzed transformation of 13( S )-HpODE to a leukotriene A-type epoxide, 8( E ),10( E )-12(13( S ))-EpODE, with its rapid nonenzymic hydrolysis on the 8-carbon to two 8,13-dihydroxy diastereomers (Scheme 38)

The severity of skin disease and joint inflammation are not related (Elsevier BV 2015

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[188] developed glutathione (GSH)-responsive polyurethane nanoparticles loaded with cisplatin, which showed GSH dose-dependent cisplatin release and significantly reduced in vitro survival of A549 lung cancer cells following the action of GSH-responsive polyurethane nanoparticles (GPUs) compared to that achieved with equal concentrations of free cisplatin