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(1984) Bile salt stimulation of colonic epithelial proliferation

Functioning as a ligand-activated transcription factor, FXR primarily binds unconjugated bile acids (BAs) like chenodeoxycholic acid (CDCA), forms a heterodimer with the retinoid X receptor (RXR), and translocates to the nucleus

Willemsen, L

Treatment for low B 12 can be by injection, with an oral supplement or a nasal spray
