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Certain peptides like gonadorelin, kisspeptin, tesamorelin, and GH secretagogues each target different parts of the HPG axis and can potentially enhance testosterone production and spermatogenesis

doi: 10.3389/fphar.2021.718147 Received 09 June 2021 Accepted 17 November 2021 Published 13 December 2021 Volume 12 - 2021 Edited by Fan Jiang, Shandong University, China Reviewed by Dechang Chen, Shanghai Jiao Tong University, China Ying Li, Xian Jiaotong University, China Updates Copyright 2021 Tepes, Gojkovic, Krezic, Zizek, Vranes, Madzar, Santak, Batelja, Milavic, Sikiric, Kocman, Simonji, Samara, Knezevic, Barisic, Lovric, Strbe, Kokot, Sjekavica, Kolak, Skrtic, Seiwerth, Boban Blagaic and Sikiric

published in the Journal of Molecular Medicine identified VEGFR2 (vascular endothelial growth factor receptor 2) activation as a central mechanism of the BPC-157 peptides pro-angiogenic effects

10.1016/0378-1119(89)90377-6 Gene 48 MutallipM.NohataN.HanazawaT.KikkawaN.HoriguchiS.FujimuraL.et al (2011)