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glutathione infection The role of (GSH) in immune modulation and defense Current Insights into Glutathione Depletion
Description
By interacting with TGFR, PDGFR can induce differentiation of MSCs into CAFs [85]

The PI3K/AKT pathway, frequently hyperactivated in cancers due to mutations like those in PIK3CA, drives metabolic reprogramming and enhances antioxidant defenses by stimulating GSH biosynthesis [49]
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Alteriis E, Carten F, Parascandola P, Serpa J, Mazzoleni S (2018) Revisiting the Crabtree/Warburg effect in a dynamic perspective: a fitness advantage against sugar-induced cell death
[DOI] [PubMed] [Google Scholar] 140.Lu C, He JC, Cai W, Liu H, Zhu L, Vlassara H
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