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204 Similarly, administration of the PRMT5 inhibitor PJ-68 in a CML mouse model with high expression of PRMT5 LSCs could deplete DVL3, thereby inhibiting Wnt/-catenin signaling and significantly prolonging the survival time of a retroviral BCR-ABL-driven CML mouse model

Previous studies have successfully utilized MRI, particularly diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) measurements, to differentiate between malignant and benign lymph node pathologies

[131] synthesized CdSe-based QDs with varying emission spectra and developed a double-analyte multiplex assay (DAM) that can simultaneously detect AFB 1 and ZEN

Low copper levels upregulate CTR1 expression to increase copper uptake, whereas high levels downregulate CTR1 expression to prevent copper cytotoxicity [27, 28]