glutathione peroxidase activity in selenium deficient rat liver The family: Discoveries and mechanism Exploring the Link between Oxidative

These ROS directly impair pancreatic -cell function by suppressing insulin gene expression (via PDX-1 inactivation) and triggering apoptosis through JNK and NF-B pathways, thereby reducing insulin secretion (Kaneto et al., 2022)

10.3389/fphar.2017.00774 43 GuoY.WangL.GouR.TangL.LiuP

Ming Cai, [email protected]

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