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For people with healthy digestion and mild deficiencies, they can be helpful

Here are some general guidelines: Mild deficiency: The typical treatment is a 250-500 mcg liquid B12 dose prescribed to patients with the mildest B12 deficiency

These micro-injuries are not visible to the naked eye, but they trigger your body's natural wound-healing response, which stimulates the production of new collagen and elastin the proteins responsible for keeping your skin firm, smooth, and youthful

And some people have B12 deficency without ever having macrocytic anaemia - even when symptoms of B12 deficency are present (30% of people present without macrocytic anaemia and some also have serum B12 levels that are within what's called 'normal' range, even before treatment is started: B12 deficiency can thus be present even if serum B12 levels appear to be normal