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Description
Research shows that in senescent cells, p53 levels are maintained low through ubiquitination while its pro-apoptotic activity is repressed through nuclear segregation by FOXO4. The peptide's competitive inhibition restores p53 activity by promoting nuclear exclusion, allowing p53 to execute its pro-apoptotic program and eliminate senescent cells through targeted pathway activation

The 10mg format allows researchers to study both arms of this dual mechanism across a full concentration gradient within a single batch, without the variability of sourcing multiple 5mg vials

Enhanced blood flow via VEGF and nitric oxide pathways may benefit uterine and ovarian function

XW: Formal Analysis, Funding acquisition, Supervision, Validation, Writing review and editing
