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One small retrospective case series investigated intra-articular BPC-157 injections for knee pain but lacked rigorous methodology, control groups, and long-term follow-up ([6])

Directed human clinical trials are necessary to validate BPC-157's efficacy in musculoskeletal injury, gastrointestinal, and vascular disorders that show promise in preclinical models

Any possible correlation with male fertility (397) seems not to have been established, though there were no negative effects (398) , and ERG improved oocyte quality and maturation in cows and sheep (399)

Serious allergic reactions (difficulty breathing, hives, facial swelling) extremely rare, seek emergency care if occurring