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Higher doses of vitamin B12 may be used to treat a clinically recognised deficiency

doi: 10.1016/j.mce.2016.09.008, 20
According to a study in 2017, cells of the hippocampus, responsible for learning and memory, are more at risk of oxidative stress than other areas

Moreover, A peptide has been used in IN delivery studies aimed at reducing A fibrils and mitigating microglial and astrocytic activation, but the clinical trials were terminated due to cases of meningoencephalitis observed in some patients [111, 192]