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To achieve the best effect, it is recommended to use the drug for 1 to 3 months, in cases of chronic diseases up to 6 months without a break

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As the pleasurable feelings of a methamphetamine high fade away, it can leave people who have developed a dependence to the drug feeling intensely unhappy, anxious, or agitated in a period of acute withdrawal colloquially known as a comedown. 1 Some people that use meth may try to maintain their high and stave off their crystal meth crash by binging, or compulsively using meth repeatedly every several hours for 315 days at a time