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When -oxidation is limited, tumors avoid ferroptosis by (i) reducing PUFA incorporation into membranes 346 , (ii) deploying extramitochondrial ubiquinol recycling to trap lipid radicals 347,348 , and (iii) using the mitochondrial dihydroorotate dehydrogenase-ubiquinone axis to detoxify lipid peroxides in the inner membrane 349
Evaluation of traditional Chinese medicine herbs in oncology clinical trials
In our work, reduction of tyrosine nitration by either nicotinamide or EGCG treatment in old age neurons suggests a combination antioxidant effect
