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Mice with a genetic ablation of GCLC exhibit embryonic lethality [56]
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A particularly compelling mechanistic extension is the proposed formation of a proteoglycan/glycosaminoglycan (GAG)-rich interface after VUV photofunctionalization, supported by (i) enrichment of heparin-/GAG-/sulfur-compoundbinding gene clusters and (ii) loss-of-function attenuation of the adhesion advantage using GAG-degrading enzymes [125]
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