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The foods highest in vitamin B12 are: Organ meats, such as beef and chicken liver Wild-caught fish, including salmon, herring, mackerel, tuna, trout and sardines (also great sources of other vital nutrients, like omega-3 fatty acids) Organic dairy products, including probiotic-rich yogurt or raw milk Pasture-raised poultry, including turkey or chicken Grass-fed beef and lamb When its not possible to get enough vitamin B12 from your diet, perhaps due to genetic conditions or taking necessary medications, someone might choose to boost intake of vitamin B12 in several ways other than receiving injections

Proc Natl Acad Sci U S A 2014;111(21):76067611

In addition, the structural properties of M cells make them suitable for their roles in IRs within the SI as these cells possess a large basolateral pocket permitting intimate contact with components of the subepithelial immune system, including dendritic cells and lymphocytes (Ohno 2016)