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In Russia, it is a registered medicine for ischaemic stroke, optic nerve disorders, and cognitive indications
97 MuscogiuriG.ChavezA.GastaldelliA.PeregoL.TripathyD.SaadM.et al (2008)

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In addition, steroid sulfate esterase (STS), another member of the SULT family, exerts an opposing activity to EST, promoting estrogenic activity through desulfurization reactions and showing widespread presence and tissue specificity in the human body [30, 31]
