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Phosphorylated Flt1 cannot significantly promote the proliferation of endothelial cells, but it can activate the actin reorganization induced by P38-MAPK of the mitogen-activated protein kinase (MAPK) family and promote the migration of endothelial cells (44), while PIGF binds to Flt-1 to increase endothelial cell proliferation by activating p38 MAPK (45)
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2.4.5.4 Mass spectrometry conditions Mass spectral parameters are shown in Table 4

The density of the suspensions ranged between 1 10 7 and 1 10 8 CFU/ml for bacteria and between 1 10 6 and 1 10 7 CFU/ml for fungi
