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Description
Genome-wide profiling of DNA-binding proteins, cleavage under targets and tagmentation (CUT&Tag-IT) CUT&Tag-IT Assay KitTissue (Active Motif, #53170) was used according to manufacturer instructions
Further MR-Egger analysis validated the lack of heterogeneity ( p = 0.564) and pleiotropy ( p = 0.800)
In addition to compromising the bacterial membrane integrity with a resulting increase in membrane permeability, the peptide also binds to the DNA and RNA and disrupts intracellular -galactosidase activity in S
(2011) Nature Medicine
