glutathione gilbert's syndrome Longer telomeres in chronic, moderate, unconjugated hyperbilirubinaemia: insights from a human study on Inherited disorders of bilirubin clearance

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This difference likely indicates that cystine starvation constitutes a more severe perturbation of cellular cysteine homeostasis than pharmacological inhibition of system x c - by erastin2 or glutamate, leading to a more rapid and extensive depletion of the intracellular cysteine pool